Rice University recently doing a sensitivity of esophageal cancer screening, in the United States and China in patients with clinical research, the researchers found, Rice University bioengineers developed a low-cost, portable, battery powered micro endoscope could eventually eliminate the need for expensive biopsy for many patients who received standard endoscopic screening of esophageal cancer.
Clinical studies involving from the United States and China 147 accept check potential malignant squamous cell carcinoma patients and to discuss the low cost of rice and high resolution optical microscope illuminated imaging system can reduce unnecessary biopsies require, when used with the traditional peep mirror light source -- global standards of nursing of esophageal cancer diagnosis.
In this study, 147 patients with suspicious lesions were examined with a conventional endoscopic light source and a rice micro endoscope. Biopsy was obtained according to the results of conventional endoscopy.
Pathological examination showed that more than half of the biopsy - fifty-eight percent - no high-grade cancer and precancerous lesions. The researchers found that endoscopic examination can be spared no need for patients with benign lesions of ninety percent. Biopsy is nervous, sometimes painful, "says lead researcher Rebecca Richards - Kortum rice Stanley C. Moore professor of biological engineering, rice 360 degrees, director of the electrical and Computer Engineering Professor: a Global Health Institute of technology." In addition, in low resource settings, the pathological costs often exceed the cost of endoscopy. So the micro endoscope can improve the prognosis of patients and provide significant cost saving advantages, if the use of the traditional endoscope light source."
Under the microscope optical fiber illumination, the cancer cells and the precancerous cells are usually different from the healthy cells. The study of cellular structure is known as histology, which usually requires an accurate diagnosis of tumor type and stage of tumor histology analysis. Determine whether biopsy for histology examination need, health professionals often use endoscope light source and a small camera installed in the flexible tube is inserted into the body to visually check of an organ or tissue without surgery can be. Rice high resolution micro endoscope using the 1-millimeter-wide microscope optical fiber cable, connected to the standard endoscopy. Cable transmission images into a high performance fluorescent microscope, and the use of a tablet computer to view the output of the microscope. Microscopic endoscopic images of the image resolution provided similar to the conventional histology and endoscopy physicians in the allowed to be suspected of malignant foci to see individual cells and nuclei.
By providing real-time histological data to the endoscope, the rice can help to remove the microscopic endoscope, otherwise it will be required for biopsy of malignant tumors. "And traditional peep mirror light source can rule the malignant tumor and eliminate the need for some patients with biopsy, in a large number of differences between malignant and benign lesions only become obvious, by histological analysis," said study co-author Dr. Sharmila anandasabapathy, Baylor College of medicine, director of the Baylor global initiative and Baylor Global Innovation center in the gastroenterology professor of medicine.
Richards's lab is engaged in the development of low-cost optical imaging and spectroscopy in Krugman, the medical point of detection of cancer and infectious diseases. Her research group is particularly interested in the development of low resource setting technology, and micro endoscope is part of this effort. It is a battery powered, low cost, requires very little training. From clinical studies, the experience and the novice endoscopy can be used to make a precise assessment of the results of endoscopic biopsy.
The clinical research plan of the rice, including cervical, bladder cancer, 12 types of oral cancer and colon cancer. "More than half of today's cancer deaths occur in developing countries, often in low resource areas," anandasabapathy said." The World Health Organization and other important international organizations has called for increased global attention to non communicable diseases, such as cancer, rice and micro endoscope is a very good example, what the right technology can change the lack of health care resources countries. "We are focus on the special LED and application module on the medical lighting and UV market.please contact us:kevin@sunerled.com or http://www.sunerled.com/English/